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【論文メモ】 RNAi関係 (2013.8.4)  

Antisense Reduction of Tau in Adult Mice Protects against Seizures.
Devos SL et al. J Neurosci. 2013
 ← Isis Pharmaceuticals社の研究者らの論文

RNA helicase A is not required for RISC activity.
Liang XH, Crooke ST. Biochim Biophys Acta. 2013
 ← Isis Pharmaceuticals社の研究者らの論文

Current Phase II proprotein convertase subtilisin/kexin 9 inhibitor therapies for dyslipidemia.
Lee P, Hegele RA. Expert Opin Investig Drugs. 2013

RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression.
Liu J et al. Nucleic Acids Res. 2013
 ← Alnylam Pharmaceuticals社の研究者らの論文

Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans.
Graham MJ et al. Circ Res. 2013
 ← Isis Pharmaceuticals社の研究者らの論文

Phase I trial of a formulated IL-12 plasmid in combination with carboplatin and docetaxel chemotherapy in the treatment of platinum-sensitive recurrent ovarian cancer.
Anwer K et al. Gynecol Oncol. 2013
 ← EGEN社の研究者らの論文

In vivo disassembly of IV administered siRNA matrix nanoparticles at the renal filtration barrier.
Naeye B et al. Biomaterials. 2013

Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge.
Zhou J et al. Mol Ther. 2013

Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice.
Aouadi M et al. Proc Natl Acad Sci U S A. 2013

How cationic lipids transfer nucleic acids into cells and across cellular membranes: recent advances.
Rehman Zu, Zuhorn IS, Hoekstra D. J Control Release. 2013

Lipid-polymer hybrid nanoparticles as a new generation therapeutic delivery platform: A review.
Hadinoto K, Sundaresan A, Cheow WS. Eur J Pharm Biopharm. 2013

Role of integrated cancer nanomedicine in overcoming drug resistance.
Iyer AK, Singh A, Ganta S, Amiji MM. Adv Drug Deliv Rev. 2013

Viral infection controlled by a calcium-dependent lipid-binding module in ALIX.
Bissig C et al. Dev Cell. 2013

Development of a novel nanoparticle by dual modification with the pluripotential cell-penetrating peptide pepfect6 for cellular uptake, endosomal escape and decondensation of an siRNA core complex.
Mitsueda A et al. Biopolymers. 2013

Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes.
Lächelt U et al. Nanomedicine. 2013

Macromolecular interactions of triterpenoids and targeted toxins: Role of saponins charge.
Thakur M et al. Int J Biol Macromol. 2013

Therapeutics targeting angiogenesis: Genetics and epigenetics, extracellular miRNAs and signaling networks (Review).
Katoh M. Int J Mol Med. 2013

FedExosomes: Engineering Therapeutic Biological Nanoparticles that Truly Deliver.
Marcus ME, Leonard JN. Pharmaceuticals (Basel). 2013

Loss and retention of RNA interference in fungi and parasites.
Nicolás FE, Torres-Martínez S, Ruiz-Vázquez RM. PLoS Pathog. 2013


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[ 2013/08/04 23:50 ] 論文メモ | TB(0) | CM(0)
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