【論文メモ】 RNAi関係 (2013.2.16)  

Surface modified HK:siRNA nanoplexes with enhanced pharmacokinetics and tumor growth inhibition.
Chou ST et al. Biomacromolecules. 2013

First-in-Man Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement.
Tabernero J et al. Cancer Discov. 2013
 ← Alnylam Pharmaceuticalsの研究者らの論文

Safe, long-term hepatic expression of anti-HCV shRNA in a nonhuman primate model.
Suhy DA et al. Mol Ther. 2012
 ← Tacere Therapeuticsの研究者の論文

Cytosolic phospholipase A2α gene silencing in the myeloid lineage alters development of Th1 responses and reduces disease severity in collagen-induced arthritis.
Courties G et al. Arthritis Rheum. 2011

Systemic Delivery of Small Interfering RNA by Use of Targeted Polycation Liposomes for Cancer Therapy.
Eriya Kenjo et al. Biol. Pharm. Bull. 2013

An RNA alternative to human transferrin: a new tool for targeting human cells.
Wilner SE et al. Mol Ther Nucleic Acids. 2012

All for one, one for all: new combinatorial RNAi therapies combat hepatitis C virus evolution.
Grimm D. Mol Ther. 2012

Comparison of Nanocomplexes with Branched and Linear Peptides for SiRNA Delivery.
Tagalakis AD et al. Biomacromolecules. 2013

Intracellular delivery and antitumor effects of pH-sensitive liposomes based on zwitterionic oligopeptide lipids.
Mo R, Sun Q, Li N, Zhang C. Biomaterials. 2013

Bioresponsive Deciduous-Charge Amphiphiles for Liposomal Delivery of DNA and siRNA.
Pierrat P et al. Pharm Res. 2013

Systemic delivery of small interfering RNA by use of targeted polycation liposomes for cancer therapy.
Kenjo E et al. Biol Pharm Bull. 2013

Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells.
Liang XH, Hart CE, Crooke ST. Biochim Biophys Acta. 2013
 ← Isis Pharmaceuticalsの研究者の論文

Gene silencing by gold nanoshell-mediated delivery and laser-triggered release of antisense oligonucleotide and siRNA.
Huschka R et al. ACS Nano. 2012

Design of multifunctional gold nanoparticles for in vitro and in vivo gene silencing.
Conde J et al. ACS Nano. 2012

Novel cell penetrating peptides with multiple motifs composed of RGD and its analogs.
Mokhtarieh AA et al. Biochem Biophys Res Commun. 2013

Efficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatform.
Gomes-da-Silva LC et al. Nanomedicine. 2013

[ 2013/02/16 14:55 ] 論文メモ | TB(0) | CM(0)

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